Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Most common passwords of 2013:
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
“This is not an excuse — this is the reality of the environment we operate in, ” Dervin said. Since 2012, JetBlue has been implementing a series of technology efforts to help it recover more quickly from bad weather. She said other tools are coming online that will help the airline keep to its schedules.
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
The pay gap has increased to 17 per cent, with women on an average of $170,000 compared with nearly $200,000 for men.
Trends and targets in antiviral phototherapy
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Novel biosensing methodologies for ultrasensitive detection of viruses
“LBS has a great student body, very diverse in terms of nationality, competitive and intelligent,” commented one American graduate from the class of 2012. “It also gave me the opportunity to study in the US [on exchange] without having to do a purely US-focused American MBA.”
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Tuesday’s event at Apple’s new Cupertino headquarters is expected to reveal its much-anticipated 10th-anniversary iPhone, offering significant upgrades to the smartphone’s display, camera and overall design.
ACE2 as a potential therapeutic target for pandemic COVID-19
South Korean activists vowed Tuesday to sneak copies of Hollywood satire "The Interview" across the border by propaganda balloon later this month, in defiance of North Korea's repeated threats.
Diagnostic technologies for COVID-19: a review
Are the political upheavals of 2016 — Brexit and America’s election of Donald Trump — a triumph of democracy or a threat to it? Democracies must respond to legitimate grievances.
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
On Thursday it published its mascot for 2016, the Year of the Monkey, and instantly it became a hit on the Internet; unfortunately some people deemed it "very ugly".
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Since the establishment of Avic 1 and Avic 2 in 1999, which really marked the beginning of China’s push into the commercial aerospace market, there has been no doubt about China’s intent and the direction it wants its industry to take. But the pace at which it would achieve this ambition was less uncertain. Almost 20 years on, things have become much more clear, and there is now little doubt that China is well on its way to succeeding where several other countries have failed in becoming a full-fledged player in the large commercial aircraft manufacturing sector, with the potential to disrupt the long-standing duopoly of Airbus and Boeing.
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
My Dear Wife
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
E-cigarettes first started becoming popular in 2012. They work by heating a nicotine fluid to mimic a real cigarette. Their invention is usually credited to Chinese pharmacist Hon Lik, who reportedly created it after he dreamed that he was drowning in a cloud of vapor. His father had died of lung cancer caused by cigarettes. He himself was an unrepentant smoker who had unsuccessfully tried quitting by using a nicotine patch.
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Antiviral drug discovery: broad-spectrum drugs from nature
Top male vocalist: Jason Aldean
Influenza neuraminidase: A druggable target for natural products
这类开发项目之一，是邓波区(Dumbo)的沃特街(Water Street)60号，一个包含290个单元的出租楼盘，带有24小时门房服务和一个可坐拥曼哈顿景观的屋顶平台。房屋租赁将于下个月开始，两居室的每月房租起价达到了令人瞠目结舌的6018美元（约合人民币3.7万元）。“人们想要体验住在共管公寓的生活，即使他们是租房而不是买房。”花旗居屋负责新开发项目的董事总经理乔迪·安·斯塔斯(Jodi Ann Stasse)说。
These larger screen sizes will put additional strain on iOS 7 and developers who will need to figure out how to adapt their apps to even more configurations. These additional formats will provide some exciting opportunities for applications as well, and we can anticipate that iOS 8 will contain many features designed to accommodate multi-screen design.
Unemployment was the most searched for financial item, followed by "Wall Street companies" and "recalls".
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Master of None
The role of biosensors in the detection of emerging infectious diseases
The central government has allocated a special fund of 100 billion yuan to provide assistance to workers laid off from overcapacity cuts, and also has asked local governments to set up matching funds.
Quantitative determination of mechanical stability in the novel coronavirus spike protein
If you want a refrigerator with a screen, might as well just stick an iPad on it. Samsung unveiled a smart refrigerator this summer that connects to wi-fi to help manage groceries and leave notes behind for family members.
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
The letter mysteriously arrived at the California University of Pennsylvania, in the north-eastern state of Pennsylvania, 10 days ago. Written to Mr Moore, the two-page letter was postmarked 20 February 1958 and signed "love forever Vonnie".
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Frances McDormand giving an outstanding central performance as a grieving mother in this darkly comic story.
A robust LinkedIn presence is crucial to any job search. You know that. Your manager knows that. And your manager probably knows that you know that – so she'll be concerned when you go from having a bare-bones profile on Monday to one jacked with additional work history, new connections, status updates and recommendations by Friday. "Don't go from zero to 500 overnight, because that can be quite obvious," Foss cautions。
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
"This is something we believe is really important for the future of our country,"Facebook (FB, Fortune 500) CEO Mark Zuckerberg said in August.
This is the sixth edition of the QS World University Rankings by Subject, featuring a record-breaking 42 disciplines, making it the largest-ever ranking of the kind. The expert opinion of the world's top 76,798 academics and 44,426 employers informed the results, alongside the analysis of 28.5 million research papers and over 113 million citations sourced from the Scopus/Elsevier bibliometric database, said QS.
Inhibition of SARS coronavirus helicase by bismuth complexes
The S&P 500’s total return of 14% this year was 40% higher than its 25-year average annual gain. Wall Street’s chief strategists spent much of the last 12 months revising their targets higher from behind. The index printed over 50 all-time record closes, with nearly all investment management professionals racing to at least pull even. A few characteristics made the U.S. stock market particularly difficult to keep up with this year.
China (mainland and Hong Kong) adds 25 to the list this year, more than any other country, for a total of 207. Three countries debut on the list this year: Mauritius, Slovakia, and Togo.
Commodity-linked sectors have been especially hard hit in recent months. Mining-sector earnings tumbled 23 per cent last year. Oil and petrochemical refiners also saw profits slammed. Despite the fall in crude prices, many refiners remain subject to crude prices agreed to before the recent price drop, even as prices for their output fall.
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
When Finnish programmer Jerry Jalava had a motorcycle accident in 2008, he faced a double tragedy. First, he lost his finger, an obvious problem for anyone who types for a living. Second, he had to deal with a medical team who thought they were comedians—learning of his profession, one surgeon joked that Jalava should go out and buy a “USB finger drive.”
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
One of the men even swoops in to give the girl a quick kiss on the cheek. He turns around in mock-embarrassment and gives his friend a hug, while the young woman speaks to her friend in French.
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Issued by the Institute of Social Security Research, Ministry of Human Resources and Social Security, the report shows that the return rate of enterprise employees' pension insurance fund reached 3.1 percent, the highest in seven years.
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
If we ask "What salary are you looking for?" say you're flexible, or say it depends on the responsibilities of the job. Try not to name a salary unless we really push you, because that gives us a leg up in the negotiating.
Cliff Stevenson, an anti-dumping expert who publishes the report based on data filed with the WTO, said the surge in US cases was driven largely by the steel industry. The increase also represented the range of countries from China to Australia, the UK and the Netherlands against which US companies were willing to file anti-dumping complaints.
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Coming of age: in the modern banlieues of Paris and in San Francisco in the 1970s. These movies dramatize the harrowing, thrilling passage to womanhood with unsparing honesty and infinite compassion.
One explanation could be that significantly more men than women work in the industry’s best-paying fields. A third of men work in private equity orventure capital, investment banking or mergers and acquisitions, andhedge funds compared with only 19 per cent of women.
Gitanjali said she wanted to further refine the device so it could eventually go on the market.
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
n. 没精打采的样子，耷拉，笨人 v. 没精打采地站，坐
The more powerful the passions and the more uncontained the ambitions, the more likely the democratic system will collapse into despotism.
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
adj. 故意的，有意的；打算中的 n. 已订婚者 v.
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Apple CEO Tim Cook
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
最佳乐队组合：Little Big Town
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
A child prodigy with an IQ higher than Albert Einstein is celebrating becoming a unique member of Mensa. Nishi Uggalle, ten, is one of the youngest people in the country to score the highest possible mark of 162 in the IQ society's supervised testing.
Though the Dutch financial markets then had none of today’s technology, they employed many of the same practices that traders use today. Investors bought securities, sometimes borrowing money with loans secured by the shares they were buying. In today's language, they bought shares on margin. Lenders protected themselves by demanding a “haircut” – collateral in cash or securities that exceeded the loan amount by a specified percentage. If the value of the securities dropped below that specified percentage, the lender would demand that the investor put up additional money to stay in line with the haircut. If the investor couldn’t come up with the added margin, the lender was entitled to liquidate the securities and recoup the loan amount.
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
The government also needs to adopt the Internet Plus governance to ensure that government services will be more easily accessible for our people.
An earlier plan by activists and the US-based Human Rights Foundation to send 100,000 copies of the film in January was postponed until after last month's Lunar New Year.
A modular microarray imaging system for highly specific COVID-19 antibody testing
Years of growth fuelled by access to cheap funding by virtue of low interest rates in the developed world and China’s robust appetite for commodities are seen ending, leading economists at the Bank of International Settlements to warn of negative spillovers as borrowing costs rise.
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
The PPI has been negative for 44 consecutive months, reflecting excess supply of housing materials and raw materials, and overcapacity in heavy industry.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
adj. 受影响的，受感动的，受疾病侵袭的 adj. 做
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Benchmark oil prices dropped below $40 a barrel last week, the lowest level in six years, darkening investor sentiment towards commodity-linked companies and exporting countries including Brazil, Russia and South Africa.
The highest scoring tournament: 1994 in theUnited Stateswhen 24 teams averaged 2.97 over 52 matches.
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Just because the job market is tough doesn't mean it's impossible. "You have to work harder at the job search," Challenger said.
根据花旗居屋(Citi Habitats)提供的数据，在布鲁克林拟于明年投放市场的6527套新出租屋中，有1442套分布在贝德福德-斯图文森(Bedford-Stuyvesant)、布什维克(Bushwick)和克林顿山(Clinton Hill)。就在不久前，这些社区都还被视为不热门的地区。
A facile assay for rapid detection of COVID-19 antibodies
The infectious disease known as scarlet fever famously reached pandemic proportions in the 19th century, striking down the young and the weak across the Western world.
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Cross-cultural Instrumental performance (Yanni, USA, and Chang Jing)
If you’re looking for a free CRM system, Zoho is probably the one for you. Why? It comes down to the integration possibilities. For example, Zoho integrates with JotForm and Unbounce simply by adding your API key. This means that within seconds, web leads will automatically be sent to your CRM. Pretty powerful for being free.
In the next few years, by 2018, theincrease to $1.3 trillion will be due to about $100 billion on hepatitis Cdrugs, the same sums spent on cancer treatment, and $78 billion on diabetescare.
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Unless Charles Oakley successfully sues owner James Dolan, the highlight of the Knicks' 2016–17 season will be Kristaps Porzingis winning the Skills Challenge at All-Star Weekend.
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Democracy is at bottom a civilised form of civil war.
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Anti-HIV drug repurposing against SARS-CoV-2
But the change in Wall Street’s — and Silicon Valley’s — appreciation of Mr Cook is down to more than just the 70m iPhones Apple is expected to sell this quarter or the $42bn in sales generated in the previous.
"Everywhere I go business owners are seeing an increase in demand," said Gus Faucher, senior economist at PNC Financial Services. "Businesses will have to raise wages to attract or maintain workers."
Length-scale dependence of protein hydration-shell density
斯特罗恩表示，他认为IP-BOX运用了和FBI没有经过苹果公司的帮助而破解塞义德·法鲁克iPhone 5c相同的技术。现在FBI已经开始向其他执法部门提供帮助解锁iPhone，iPad或者iPod Touch的方法。苹果方面正在积极寻找FBI是如何破解iPhone的，并将推出软件更新来关闭这些漏洞。
About 40 per cent of entrepreneurs did not seek any help when securing finance. Half of these raised equity purely from their own savings and/or family and friends compared with only 40 per cent of those who sought help from the school or alumni network.
Another slowdown in food prices pulled Chinese inflation lower in October, according to the National Bureau of Statistics.
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Li Xiaojin, a professor at Civil Aviation University of China's Economics and Management College, said that rapidly increasing numbers of flights and limited airspace for civil aviation are the major reasons for delays.
5.ah, you look great in that dress. – Because it’s better than being slapped。
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
Well, that’s it, kids: we’re heading home. Chinese shares are down 7 per cent, and thanks to the newly-instituted market circuit breakers, that means the market shuts.
About this collection
But that idea did not bring Brexit to the UK or Mr Trump to Washington.
But the temperature of 1998 is now being surpassed every four or five years, and 2014 was the first time that happened without a significant El Ni?o. Gavin A. Schmidt, head of NASA’s Goddard Institute for Space Studies in Manhattan, said the next strong El Ni?o would probably rout all temperature records.