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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

交通银行首席经济学家连平表示,不断上涨的生产者物价可能会在较长的时间内推高消费价格。
比蒂和唐纳薇上台宣布最佳影片奖时,卡利南和瑞兹意识到他们手里还有两只最佳影片信封,也就是说,拿上台的信封是已经宣布过的奖项。

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
From the themed collection: 北京城市文化竞争力全国居首
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

许多管理者提到了一些极其失礼的情况。求职者:
Most common passwords of 2013:

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

她说:“1到10,我觉得自己只能拿9分,因为我一定还有提升的空间。我知道我可以走更远。”

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

“This is not an excuse — this is the reality of the environment we operate in, ” Dervin said. Since 2012, JetBlue has been implementing a series of technology efforts to help it recover more quickly from bad weather. She said other tools are coming online that will help the airline keep to its schedules.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

减薪前奥朗德的年收入为25.56万欧元(约合27万4522美元),仅次于美国总统奥巴马。但现在他的年收入仅为19.87万美元。众所周知,他的御用理发师年收入高达13.2万美元。
Project management.
“现在黑客使用流行文化或体育活动中的常见说法来破解网上账户,因为他们知道很多人在使用这些容易记住的词做密码。”
The pay gap has increased to 17 per cent, with women on an average of $170,000 compared with nearly $200,000 for men.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

潘通在解释这一选择时提到以下这些因素:“主张性别平等和流动性的社会运动;消费者越来越喜欢把色彩当作一种表达方式;这一代人不太在意被认定为某一种类型或遭到评判;公开的数字信息交流让我们看到颜色使用的不同方式。”
nutrition
vigil醒着的+ance表名词,“性质,状况”→警惕
上周五,中国汽车制造协会宣布,1月份的乘用车销量达到220万台,比去年同期增长了9.3%,同时,新能源汽车的产量则激增了144%。

Graphical abstract: Trends and targets in antiviral phototherapy
From the themed collection: 北京商住房限购两年成交量下跌94%
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

当其他同龄人每天乖乖去上学的时候,她已经出来养家糊口四年了,她不得不快速成熟起来。

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

“LBS has a great student body, very diverse in terms of nationality, competitive and intelligent,” commented one American graduate from the class of 2012. “It also gave me the opportunity to study in the US [on exchange] without having to do a purely US-focused American MBA.”

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

Tuesday’s event at Apple’s new Cupertino headquarters is expected to reveal its much-anticipated 10th-anniversary iPhone, offering significant upgrades to the smartphone’s display, camera and overall design.
Regional

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

BrandZ表示,这些品牌靠近国内市场,这帮助它们从全球品牌手中夺取市场份额,它们还在新地区赢得市场份额。
South Korean activists vowed Tuesday to sneak copies of Hollywood satire "The Interview" across the border by propaganda balloon later this month, in defiance of North Korea's repeated threats.

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

Are the political upheavals of 2016 — Brexit and America’s election of Donald Trump — a triumph of democracy or a threat to it? Democracies must respond to legitimate grievances.
对欧洲的新投资比2014年的180亿美元高出28%,相比之下,2014年投资额较2013年翻了一倍。对美国的投资比2014年的128亿美元高出17%。

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

On Thursday it published its mascot for 2016, the Year of the Monkey, and instantly it became a hit on the Internet; unfortunately some people deemed it "very ugly".
当年的荷兰金融市场固然没有今天的任何科技,但他们的很多做法都和今天的交易员一样。投资者们买入证券,有时会用买入的股票质押获得贷款。用今天的话说,他们基于保证金买入股票。贷款机构为了自身安全,会要求一个超出贷款金额一定百分比的“折幅”,质押现金或证券。如果证券价格下跌超过一定幅度,贷款机构会要求投资者交出更多资金,与“折幅”保持一致。如果投资者拿不出追加保证金,贷款机构有权将证券平仓,收回贷款额。
中国香港——也许香港的标志性景观是一艘驶入画面的仿古船,其背景正是这座城市举世闻名的天际线,但《孤独星球》选中此地却是因为距维多利亚港数英里之外的自然遗产。
2. 美国页岩油。截至2014年底,美国页岩油日产量已经超过900万桶,比2007年增加了80%。这些页岩油是造成石油供给过剩的主要力量,而供过于求是2014年油价暴跌的诱因之一。总的来说,美国页岩油开采公司都搬起石头砸了自己的脚,但关键在于,西德州轻质低硫原油(WTI)价格跌破60美元对它们有何影响?页岩油钻机数量不断减少,相关开支也遭到削减,然而到目前为止,美国页岩油产量依然稳定。按照当前油价,这个行业能否维持产出水平,或者说美国页岩油产量会不会减少将对国际市场供应乃至油价产生重大影响。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

Since the establishment of Avic 1 and Avic 2 in 1999, which really marked the beginning of China’s push into the commercial aerospace market, there has been no doubt about China’s intent and the direction it wants its industry to take. But the pace at which it would achieve this ambition was less uncertain. Almost 20 years on, things have become much more clear, and there is now little doubt that China is well on its way to succeeding where several other countries have failed in becoming a full-fledged player in the large commercial aircraft manufacturing sector, with the potential to disrupt the long-standing duopoly of Airbus and Boeing.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

My Dear Wife
户外空间:该房产占地面积接近1.5英亩(约6070平方米)。

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

E-cigarettes first started becoming popular in 2012. They work by heating a nicotine fluid to mimic a real cigarette. Their invention is usually credited to Chinese pharmacist Hon Lik, who reportedly created it after he dreamed that he was drowning in a cloud of vapor. His father had died of lung cancer caused by cigarettes. He himself was an unrepentant smoker who had unsuccessfully tried quitting by using a nicotine patch.

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

无论你相信与否,今年的搞笑文学奖被授予美国政府审计总署(GAO),以表彰他们发表的有关如何准备一份报告的报告的报告的报告……

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

Top male vocalist: Jason Aldean
最令人兴奋地其实是交易期
['temp?r?ri]
每季度,英特尔(Intel)都会铺上红地毯,欢迎加入公司的新员工。在入职培训的第一天,每位新人都会受到摄影师和摄像师的夹道欢迎,上台做完自我介绍,新人们就能领取一份欢迎大礼包(还有周围新同事们的热烈掌声)。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

这类开发项目之一,是邓波区(Dumbo)的沃特街(Water Street)60号,一个包含290个单元的出租楼盘,带有24小时门房服务和一个可坐拥曼哈顿景观的屋顶平台。房屋租赁将于下个月开始,两居室的每月房租起价达到了令人瞠目结舌的6018美元(约合人民币3.7万元)。“人们想要体验住在共管公寓的生活,即使他们是租房而不是买房。”花旗居屋负责新开发项目的董事总经理乔迪·安·斯塔斯(Jodi Ann Stasse)说。
These larger screen sizes will put additional strain on iOS 7 and developers who will need to figure out how to adapt their apps to even more configurations. These additional formats will provide some exciting opportunities for applications as well, and we can anticipate that iOS 8 will contain many features designed to accommodate multi-screen design.
2016的很多电影都会有很好的票房号召力,但人们迫不及待想要观看的其实只有那么几部。
尽管与普通的开瓶器并无二致,但它拥有精良的设计,是由不锈钢和实木制成的。
Unemployment was the most searched for financial item, followed by "Wall Street companies" and "recalls".

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

他还表示“包括现代汽车(Hyundai Motor)和爱茉莉太平洋(AmorePacific)在内,几乎每家韩国大企业都严重依赖对华销售。”
Master of None

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
From the themed collection: 2015年“中国·水头石材指数”看点
Critical Review

The role of biosensors in the detection of emerging infectious diseases

The central government has allocated a special fund of 100 billion yuan to provide assistance to workers laid off from overcapacity cuts, and also has asked local governments to set up matching funds.

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

If you want a refrigerator with a screen, might as well just stick an iPad on it. Samsung unveiled a smart refrigerator this summer that connects to wi-fi to help manage groceries and leave notes behind for family members.

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

中国品牌上榜主要是挤掉了欧洲企业,这表明,经济实力正向东方转移。只有一家印度品牌登上百强榜:HDFC Bank。过去几年,俄罗斯、墨西哥和巴西品牌纷纷落榜,这残酷反映出这些新兴市场的命运正发生变化。
extend
The letter mysteriously arrived at the California University of Pennsylvania, in the north-eastern state of Pennsylvania, 10 days ago. Written to Mr Moore, the two-page letter was postmarked 20 February 1958 and signed "love forever Vonnie".
在过去的12个月里,这位22岁的T台女王兼真人秀明星赚得2200万美元,首次登顶福布斯模特收入榜。

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

因此,他在福布斯的该榜单上排名下滑了220位,与其他19名富豪并列第544位。
政治建军、改革强军、依法治军
Frances McDormand giving an outstanding central performance as a grieving mother in this darkly comic story.
A robust LinkedIn presence is crucial to any job search. You know that. Your manager knows that. And your manager probably knows that you know that – so she'll be concerned when you go from having a bare-bones profile on Monday to one jacked with additional work history, new connections, status updates and recommendations by Friday. "Don't go from zero to 500 overnight, because that can be quite obvious," Foss cautions。

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

"This is something we believe is really important for the future of our country,"Facebook (FB, Fortune 500) CEO Mark Zuckerberg said in August.
This is the sixth edition of the QS World University Rankings by Subject, featuring a record-breaking 42 disciplines, making it the largest-ever ranking of the kind. The expert opinion of the world's top 76,798 academics and 44,426 employers informed the results, alongside the analysis of 28.5 million research papers and over 113 million citations sourced from the Scopus/Elsevier bibliometric database, said QS.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

The S&P 500’s total return of 14% this year was 40% higher than its 25-year average annual gain. Wall Street’s chief strategists spent much of the last 12 months revising their targets higher from behind. The index printed over 50 all-time record closes, with nearly all investment management professionals racing to at least pull even. A few characteristics made the U.S. stock market particularly difficult to keep up with this year.
问:最后一个问题——在你的许多作品中,你总以强烈的感情质疑正义,质疑英雄主义是否道德。那么你对于成为英雄这种事是怎么看的呢?
China (mainland and Hong Kong) adds 25 to the list this year, more than any other country, for a total of 207. Three countries debut on the list this year: Mauritius, Slovakia, and Togo.
作为历史上一种非常敏感的大宗商品,原油价格走势已连续三年保持波澜不惊,其背后的一大支持因素就是美国的页岩油。
Commodity-linked sectors have been especially hard hit in recent months. Mining-sector earnings tumbled 23 per cent last year. Oil and petrochemical refiners also saw profits slammed. Despite the fall in crude prices, many refiners remain subject to crude prices agreed to before the recent price drop, even as prices for their output fall.

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

When Finnish programmer Jerry Jalava had a motorcycle accident in 2008, he faced a double tragedy. First, he lost his finger, an obvious problem for anyone who types for a living. Second, he had to deal with a medical team who thought they were comedians—learning of his profession, one surgeon joked that Jalava should go out and buy a “USB finger drive.”
她说:“我们一直在寻找他的遗骨,终于找到了。现在是为他恢复名誉的时候了。”
但事实上,作为一项新技术以及新运动,比特币在2014年表现出了猛烈的势头,而且在新的一年有望征服更多怀疑论者。诸多领域的指标证明了这一点:与比特币相关的初创企业和就业岗位数量大增;接受比特币的机构数量也大大增加;开发人员间的活动也较此前增强。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

以下是我们精选的本届科隆游戏展最值得关注的新游戏。
《静待黎明》

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
From the themed collection: 沙河11条玻璃线开建脱硫除尘设施
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

adv. 有意地,故意地
7. 2012年搞笑诺贝尔奖之物理学奖
One of the men even swoops in to give the girl a quick kiss on the cheek. He turns around in mock-embarrassment and gives his friend a hug, while the young woman speaks to her friend in French.

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

你的老板很差
胡润估计,如果此举获得成功,王健林的净财富可能会猛增至逾500亿美元,令他跻身世界前十大富豪之列。
如果说2017年是政策制定者们开始担心“无保障无产阶级”(precariat)人数增长的一年,那么2018年将是他们尝试为此做些什么的一年。

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

特约专栏作家安东尼·盖尔恩是Paragon欧洲合作伙伴的常务董事。目前位于伦敦。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
From the themed collection: 细数中国陶瓷行业十八怪
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

Issued by the Institute of Social Security Research, Ministry of Human Resources and Social Security, the report shows that the return rate of enterprise employees' pension insurance fund reached 3.1 percent, the highest in seven years.

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

If we ask "What salary are you looking for?" say you're flexible, or say it depends on the responsibilities of the job. Try not to name a salary unless we really push you, because that gives us a leg up in the negotiating.
Cliff Stevenson, an anti-dumping expert who publishes the report based on data filed with the WTO, said the surge in US cases was driven largely by the steel industry. The increase also represented the range of countries from China to Australia, the UK and the Netherlands against which US companies were willing to file anti-dumping complaints.

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

Coming of age: in the modern banlieues of Paris and in San Francisco in the 1970s. These movies dramatize the harrowing, thrilling passage to womanhood with unsparing honesty and infinite compassion.
One explanation could be that significantly more men than women work in the industry’s best-paying fields. A third of men work in private equity orventure capital, investment banking or mergers and acquisitions, andhedge funds compared with only 19 per cent of women.
传统佳节之际,献上殷殷祝福,祝新年万事如意!
Gitanjali said she wanted to further refine the device so it could eventually go on the market.

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

n. 没精打采的样子,耷拉,笨人 v. 没精打采地站,坐
The more powerful the passions and the more uncontained the ambitions, the more likely the democratic system will collapse into despotism.

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

adj. 故意的,有意的;打算中的 n. 已订婚者 v.
印度国家板球队

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

曼谷王者归来!

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

大小:6364平方英尺(约591平方米)
1.Nepal
单词reflection 联想记忆:
这些正在修建一座足球场的工人在巴格达东北部什叶派穆斯林聚居的哈比比亚城区被绑架。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

为了缓解人口过多的问题,科学家研究出一项技术,可以将人缩小到只有5英寸高(12.7cm)。保罗(马特?达蒙饰)和妻子奥德丽(克里斯汀?韦格饰)决定把紧巴巴的生活抛在身后,自愿缩身加入一个全新的迷你社区。这一决定使得这对夫妇的人生发生了翻天覆地的变化。
Apple CEO Tim Cook

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

jail
《二十二》讲述的是22名慰安妇的故事,是中国首部票房超过1亿元的纪录片。
最佳乐队组合:Little Big Town

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

A child prodigy with an IQ higher than Albert Einstein is celebrating becoming a unique member of Mensa. Nishi Uggalle, ten, is one of the youngest people in the country to score the highest possible mark of 162 in the IQ society's supervised testing.
Though the Dutch financial markets then had none of today’s technology, they employed many of the same practices that traders use today. Investors bought securities, sometimes borrowing money with loans secured by the shares they were buying. In today's language, they bought shares on margin. Lenders protected themselves by demanding a “haircut” – collateral in cash or securities that exceeded the loan amount by a specified percentage. If the value of the securities dropped below that specified percentage, the lender would demand that the investor put up additional money to stay in line with the haircut. If the investor couldn’t come up with the added margin, the lender was entitled to liquidate the securities and recoup the loan amount.
曾在许多公司里面工作过----大公司或小公司----我看到过很多的方法有些起作用,有些并不起作用。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

morality
像中国人口这么多的国家,关于寂寞的病毒式模仿会这么流行实在是件很讽刺的事情。这句看上去很无厘头的话被用在了所有可能搭配的排列中,用在了所有场合,比如,“哥看的不是书,是寂寞。”

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

它把孩子的重量从您的后背转移到肩膀和腰腹部。
The government also needs to adopt the Internet Plus governance to ensure that government services will be more easily accessible for our people.
An earlier plan by activists and the US-based Human Rights Foundation to send 100,000 copies of the film in January was postponed until after last month's Lunar New Year.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

卓越雇主排名:32
Years of growth fuelled by access to cheap funding by virtue of low interest rates in the developed world and China’s robust appetite for commodities are seen ending, leading economists at the Bank of International Settlements to warn of negative spillovers as borrowing costs rise.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

日本总体排名第五,是亚洲表现最优异的国家。“原动力”排名第五,“前瞻性”排名第一。
怎么玩扑克?
艾丽斯·斯瓦策尔(Alice Schwarzer)

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

8. 2012年搞笑诺贝尔奖之流体力学奖

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

发布日期:2015年春季
The PPI has been negative for 44 consecutive months, reflecting excess supply of housing materials and raw materials, and overcapacity in heavy industry.

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

切实落实脱贫攻坚责任制,实施最严格的评估考核,严肃查处假脱贫、“被脱贫”、数字脱贫,确保脱贫得到群众认可、经得起历史检验。
adj. 受影响的,受感动的,受疾病侵袭的 adj. 做

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

Benchmark oil prices dropped below $40 a barrel last week, the lowest level in six years, darkening investor sentiment towards commodity-linked companies and exporting countries including Brazil, Russia and South Africa.
The highest scoring tournament: 1994 in theUnited Stateswhen 24 teams averaged 2.97 over 52 matches.

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

Just because the job market is tough doesn't mean it's impossible. "You have to work harder at the job search," Challenger said.
根据花旗居屋(Citi Habitats)提供的数据,在布鲁克林拟于明年投放市场的6527套新出租屋中,有1442套分布在贝德福德-斯图文森(Bedford-Stuyvesant)、布什维克(Bushwick)和克林顿山(Clinton Hill)。就在不久前,这些社区都还被视为不热门的地区。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

The infectious disease known as scarlet fever famously reached pandemic proportions in the 19th century, striking down the young and the weak across the Western world.

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

我认为这篇文章是上篇文章“成为一个足球寡妇”的完美续篇,在这篇文章里面我分享了八大规则,其中我觉得第六条最重要。
Cross-cultural Instrumental performance (Yanni, USA, and Chang Jing)
If you’re looking for a free CRM system, Zoho is probably the one for you. Why? It comes down to the integration possibilities. For example, Zoho integrates with JotForm and Unbounce simply by adding your API key. This means that within seconds, web leads will automatically be sent to your CRM. Pretty powerful for being free.
In the next few years, by 2018, theincrease to $1.3 trillion will be due to about $100 billion on hepatitis Cdrugs, the same sums spent on cancer treatment, and $78 billion on diabetescare.

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

Sarah Collins

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

站在舞台中央,莱昂纳多发言说:“这是无上的荣誉,对我意义重大。两年前当我们置身于荒野当中拍摄电影,我们深深地被大自然的美丽和庞杂所感染。
当新员工迈入QuikTrip位于塔尔萨的总部时,他们可没功夫去害羞:刚开始的几天,他们的办公桌上都摆着满满一大桶糖果。路过的同事常常停下来做自我介绍,顺手也抓块糖吃。
Unless Charles Oakley successfully sues owner James Dolan, the highlight of the Knicks' 2016–17 season will be Kristaps Porzingis winning the Skills Challenge at All-Star Weekend.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

你可能觉得夏威夷航空的运营相对容易,因为该公司的航班很少遇到美国大陆那种恶劣的天气条件。夏威夷航空公司在航班准点率排行榜上常年位居前列,在9月份最新公布的榜单上创下最高准点率。夏威夷航空公司最近宣布将把业务拓展到夏威夷岛外,开通从檀香山到北京的直达航班。
经济学家原本还预计,今年1至10月份全国固定资产投资(不含农户)增长速度会与1至9月份的增长速度8.2%持平。

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

“我们做事情不是为了追求利润,我们做事情,是因为这些事情是正确和公正的,”库克咆哮道。他说,不管是为了人权、可再生能源还是为有特殊需求的人们提供帮助,“我不考虑该死的投资回报率”。“直截了当地跟你说,如果这是你考虑的硬性因素……那你还是把苹果股票卖了吧。”库克的语气严厉,毫不妥协,那是苹果员工或许永远不希望面对的一个声音。
Democracy is at bottom a civilised form of civil war.

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

凯莎《彩虹》

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
From the themed collection: 下一轮调控重点须从房价转向地价
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

Vawter 使用仿生腿在芝加哥一栋高楼里向上爬了103个阶梯,但是仿生腿的设计者们仍然在尝试提高它的性能。为了使它能适用于日常生活,设计者们必须让它更轻更薄。它的衍生品(充气仿生腿)可以满足陆军对于仿生腿的阶段性目标——行走一万步不用充电。
But the change in Wall Street’s — and Silicon Valley’s — appreciation of Mr Cook is down to more than just the 70m iPhones Apple is expected to sell this quarter or the $42bn in sales generated in the previous.
"Everywhere I go business owners are seeing an increase in demand," said Gus Faucher, senior economist at PNC Financial Services. "Businesses will have to raise wages to attract or maintain workers."

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

斯特罗恩表示,他认为IP-BOX运用了和FBI没有经过苹果公司的帮助而破解塞义德·法鲁克iPhone 5c相同的技术。现在FBI已经开始向其他执法部门提供帮助解锁iPhone,iPad或者iPod Touch的方法。苹果方面正在积极寻找FBI是如何破解iPhone的,并将推出软件更新来关闭这些漏洞。
该项目曾在2006年荣获亚军,并在2008年斩获冠军头衔。
About 40 per cent of entrepreneurs did not seek any help when securing finance. Half of these raised equity purely from their own savings and/or family and friends compared with only 40 per cent of those who sought help from the school or alumni network.
Another slowdown in food prices pulled Chinese inflation lower in October, according to the National Bureau of Statistics.

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

Li Xiaojin, a professor at Civil Aviation University of China's Economics and Management College, said that rapidly increasing numbers of flights and limited airspace for civil aviation are the major reasons for delays.
5.ah, you look great in that dress. – Because it’s better than being slapped。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
From the themed collection: 揭露家装建材业八大谣言
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

201512/415505.shtml
11月,中国的出口总值增速是预期的2倍多,这增加了中国的贸易顺差。
Well, that’s it, kids: we’re heading home. Chinese shares are down 7 per cent, and thanks to the newly-instituted market circuit breakers, that means the market shuts.

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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But that idea did not bring Brexit to the UK or Mr Trump to Washington.
But the temperature of 1998 is now being surpassed every four or five years, and 2014 was the first time that happened without a significant El Ni?o. Gavin A. Schmidt, head of NASA’s Goddard Institute for Space Studies in Manhattan, said the next strong El Ni?o would probably rout all temperature records.

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